Megabus in the US

[barber2384]

So I am beginning to plan our honeymoon for next September of which we are exploring a few states in the US using various means of transportation, one of which we are very much interested in is Megabus as it is cheap, easy and allows us to see proper America instead of just flying everywhere. Just wondered though, is there any negatives to this service? We are hiring a car for some of our trip later on but wanted to have a variety of transport hence why we are looking at this.

The legs we were potentially looking at were:

New York to Washington DC
And
Las Vegas to Anaheim