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Old 18 Oct 20, 10:19 PM  
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#21
neilhd
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I think with T Cells you must be infected before they are summoned as they kill off cells that have been infected (unlike antibodies which stop cells getting infected).

Our high-cycle PCR tests are likely to pick up the remains.

So I guess there are 3 likely outcomes:

1 - you have a false negative
2 - you have some other innate immunity
3 - you simply arenít infected!
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Old 18 Oct 20, 10:38 PM  
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I had symptoms about 5 weeks ago. Spent 4 days trying to get a test to no avail so I still have no idea. DH is asthmatic. We just stayed away from everyone but he didn't shield at all from me. He has had no symptoms at all. I'm wondering if I should bother to try for a test at all now!
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Old 19 Oct 20, 12:27 AM  
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Originally Posted by neilhd View Post
I think with T Cells you must be infected before they are summoned as they kill off cells that have been infected (unlike antibodies which stop cells getting infected).

Our high-cycle PCR tests are likely to pick up the remains.

So I guess there are 3 likely outcomes:

1 - you have a false negative
2 - you have some other innate immunity
3 - you simply arenít infected!
Innate immunity is a complex process, interferons produce T Cells, and NK (Natural Killer) cells. So the T cell response is part of the innate immunity response.

Hereís a prof who studies this area and says there are people recovering without displaying antibodies because of the innate immunity response:

labnews/article/20...ovid-19-combat

Interesting stuff.

I suspect many more of us will have innate immunity than realised.
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Old 19 Oct 20, 03:13 AM  
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Originally Posted by cornishfrogboy View Post
We are a family of 4.

I work in an office of 11. 3 of us tested positive.

When I had my test (Positive), the wife and my sons went.. negative.

A week later, my wife tested again.. Positive, but again the boys were negative.

We took no precautions at all in the office. We took no precautions at all in the home. My remaining workmates (8) and sons (2) have never had a positive test.

My only conclusion can be that it is nowhere near as easily transmitted as is frequently suggested.. or all 10 had T Cell immunity.
I also agree. Its like HIV. Thats ridiculously hard for some to catch and they liken potential immunity to T cells having been triggered in the past
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Old 19 Oct 20, 08:23 AM  
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Originally Posted by cornishfrogboy View Post
We are a family of 4.

I work in an office of 11. 3 of us tested positive.

When I had my test (Positive), the wife and my sons went.. negative.

A week later, my wife tested again.. Positive, but again the boys were negative.

We took no precautions at all in the office. We took no precautions at all in the home. My remaining workmates (8) and sons (2) have never had a positive test.

My only conclusion can be that it is nowhere near as easily transmitted as is frequently suggested.. or all 10 had T Cell immunity.
Remember you can have this and not spread it, you can also have it and display no visible symptoms.

Maybe your kids had it back in early March and everyone wrote it off as a cold; but through luck (as you were trying to avoid getting their cold) you didn't contract CV then.

When you did they were already able to fight the virus.

Not saying it happened like that just that it could have...
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Old 19 Oct 20, 08:56 AM  
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Originally Posted by 123 View Post
Remember you can have this and not spread it, you can also have it and display no visible symptoms.

Maybe your kids had it back in early March and everyone wrote it off as a cold; but through luck (as you were trying to avoid getting their cold) you didn't contract CV then.

When you did they were already able to fight the virus.

Not saying it happened like that just that it could have...
That is possible and has been considered. The kids Covid could have predated ours, been asymptomatic and also could have been passed by them onto us. They would then have tested negative by the time we tested positive.

We all four of us had that horrible, snotty common cold in January that many believe was when they had Covid (but were not tested). It has been suggested that for some, this gave strong immunity against Covid at a later date. This might have explained why in May, when we actually had it (positive tests), it was very mild. If it wasnít Covid, neither of us would have taken a day off work.
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Old 19 Oct 20, 08:58 AM  
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Originally Posted by 123 View Post
Remember you can have this and not spread it, you can also have it and display no visible symptoms.

Maybe your kids had it back in early March and everyone wrote it off as a cold; but through luck (as you were trying to avoid getting their cold) you didn't contract CV then.

When you did they were already able to fight the virus.

Not saying it happened like that just that it could have...
That is possible and has been considered. The kids Covid could have predated ours, been asymptomatic and also could have been passed by them onto us. They would then have tested negative by the time we tested positive.

We all four of us had that horrible, snotty common cold in January that many believe was when they had Covid (but were not tested and therefore do not know). It has been suggested that for some, this gave strong immunity against Covid infection at a later date. This might have explained why in May, when we actually had it (positive tests), it was very mild. If it wasnít Covid, neither of us would even have taken a day off work. (We tend to attend work if anything short of hospitalised).
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Old 19 Oct 20, 11:15 AM  
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Weíre exactly the same. Dh is positive and myself and 2 sons are negative. Very strange
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Old 20 Oct 20, 08:12 PM  
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Could it be a reliability issue with how the test is done. Iíve heard if you donít go down the throat enough for up the nose enough it will come back a false negative. 🤷
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Old 21 Oct 20, 01:29 PM  
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Originally Posted by Clairelovestate View Post
Could it be a reliability issue with how the test is done. Iíve heard if you donít go down the throat enough for up the nose enough it will come back a false negative. 🤷
They did say before a lot of people weren't doing them incorrectly as not going up the nose enough or not getting the tonsils. It's understandable as it's not a simple swab. I'm not sure how I'd get on if did one.

There could be a lot of false negatives as a results.
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