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Old 20 Jul 21, 11:27 AM  
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Scotty
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PCR test question Updated with official answer.

What happens if you have a positive PCR test then 24 hrs later have a negative one?
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Old 20 Jul 21, 11:44 AM  
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Omega1
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Originally Posted by Scotty View Post
What happens if you have a positive PCR test then 24 hrs later have a negative one?
Best of 3?😉
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Old 20 Jul 21, 11:50 AM  
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next one the winner?
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Old 20 Jul 21, 11:52 AM  
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Jakey Neverland
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Quite normal as LFT often give false negs. You would still need a PCR to confirm the positive. My daughter was pos LFT, pos PCR and got a neg LFT 2 days later. They say not to retest for 90 days after having covid due to it not being accurate.
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Old 20 Jul 21, 11:59 AM  
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Originally Posted by Scotty View Post
What happens if you have a positive PCR test then 24 hrs later have a negative one?
Why would you do PCR twice?
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Old 20 Jul 21, 12:22 PM  
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Scotty
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Originally Posted by Bellasmummy View Post
Why would you do PCR twice?
Because it was done by a private employer, they did 3, 1st 2 were inconclusive, 3rd was lost initially then reported as positive.
After all that we aren't confident of the lab.
Getting an NHS one done locally to see what result it gives.
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Old 20 Jul 21, 03:05 PM  
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sky13
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Some scenarios I can think of where you would get a positive PCR result followed by a negative PCR result 24 hours later:

1) Acute infection, where the negative PCR result is a false negative. This could be due to any number of factors including how well the sample was collected, were there any issues with transport/storage of the sample.

2) Not infected, where the positive PCR result is a false positive. This is rare but can very occasionally happen due to various reasons (no test has 100% specificity).

3) Previous infection, with prolonged viral shedding. With this the amount of viral genetic material is usually quite low and may be close to the limit of detection of the test - so it's very possible for someone with this to test positive negative negative positive etc.
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Old 20 Jul 21, 06:01 PM  
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False positives and false negatives are possible, false positives are more likely (but still pretty uncommon). In fact they may not be false positives in the truest sense, they're often when the test is so sensitive it has picked up dead virus RNA from an old infection. Equally, false negatives are often when the sample has not been collected correctly.

Someone joked best of 3 but I've heard worse ideas. Or you could try and contact your local public health department for advice.
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Old 20 Jul 21, 06:11 PM  
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Scotty
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Thanks folks.
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Old 22 Jul 21, 12:25 PM  
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Scotty
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In case anyone is interested, the official answer that has just been received from NHS Scotland track and trace was that there is no need to isolate.
Carry on as normal😁
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